Schizophrenia and Other Psychoses
Paranoia is one of the most common adverse reactions to marijuana anxiety. Paranoia appears to be a more familiar feeling with larger doses of marijuana. Like anxiety, because marijuana affects all users differently and many factors come into play with marijuana use, consistent data are challenging to achieve.
Supporting Articles
Behavioral, cognitive and psychophysiological effects of cannabinoids
Sewell, R. A., Skosnik, P. D., Garcia-Sosa, I., Ranganathan, M., & D’Souza, D. C. (2010). Behavioral, cognitive and psychophysiological effects of cannabinoids: Relevance to psychosis and schizophrenia. Brazilian Journal of Psychiatry, 32(suppl 1), 515-530. https://doi.org/10.1590/S1516-44462010000500005
Marijuana use in the immediate 5-year premorbid period is associated with increased risk of onset
Kelley, M. E., Wan, C. R., Broussard, B., Crisafio, A., Cristofaro, S., Johnson, S., Reed, T. A., Amar, P., Kaslow, N. J., Walker, E. F., & Compton, M. T. (2016). Marijuana use in the immediate 5-year premorbid period is associated with increased risk of onset of schizophrenia and related psychotic disorders. Schizophrenia Research, 171(1-3), 62-67. https://doi.org/10.1016/j.schres.2016.01.015